THCA is a non-psychoactive cannabinoid that converts into THC through heating (via smoking, vaping, dabbing, or cooking for edibles). Once heated, THCA’s extra carboxyl ring transforms into the psychoactive THC. THCA has anti-inflammatory and neuroprotective benefits and is effective for pain relief, appetite stimulation, and nausea reduction. It also has anti-proliferative properties and may inhibit the growth of cancer cells.
THCA is the Non-Psychoactive Precursor to THC
The main difference between THCA and THC is that THCA is non-psychoactive in its raw form, while THC is psychoactive. THCA has an extra molecular carboxyl group that keeps it from binding to the brain’s receptors and causing the high associated with THC. Despite not getting you high, THCA still provides numerous therapeutic benefits. It can reduce pain (possibly more effectively than CBD), promote sleep, and act as an appetite stimulant. THCA has neuroprotective qualities that may help slow the progression of degenerative diseases.
Heat causes the conversion of THCA into THC. This process is called decarboxylation. Decarboxylation is also the process of making edibles from cannabis plants. It is important to remember that THCA will also convert into THC-COOH, a cannabinoid that can appear on drug tests. Because of this, it is crucial to follow the dosage recommendations on your products carefully. Generally, you will want to start low and work up to a dose that feels comfortable for you. Also, it is important to know that consuming THC-COOH can cause you to fail a drug test at work or school. It is because most workplaces have cut-off levels for THC in the bloodstream.
THCA Has a Carboxylic Acid Group
THCA can’t get you high because it has an extra molecular carboxyl group that prevents the cannabinoid from binding to CB1 receptors in your brain. The carboxyl group can be removed by decarboxylation, done through heat exposure such as smoking, vaping, dabbing and cooking for edibles. While THCA doesn’t produce any psychoactive effects, it does have many therapeutic qualities. For example, a high-THCA flower can increase appetite and improve nausea. It can also reduce pain perception and inflammation. THCA’s anti-inflammatory properties may help treat conditions like arthritis and fibromyalgia. THCA also has neuroprotective properties, according to various studies. The cannabinoid activates the PPARg receptor, which slows down or even stops the progression of neurodegenerative diseases such as Alzheimer’s. THCA can be consumed in raw cannabis, such as juices and tinctures. However, the cannabinoid is most commonly decarboxylated through heating to produce THC.
THCA Is More Active than CBD
As a non-psychoactive precursor to THC, THCA has unique therapeutic properties that are being explored. It may have anti-inflammatory, appetite stimulant, and neuroprotective qualities. THCA has also been found to help relieve nausea and suppress tumors in lab tests. Some studies have even shown that THCA when consumed with CBD, can provide a greater therapeutic effect than either compound alone. It is called the entourage effect and is believed to be due to the interaction between different cannabinoids. In addition to boosting the effectiveness of CBD, THCA can reduce or eliminate the psychoactive effects of THC. THCA can be smoked or vaporized in cannabis products like a bud bowl or joint, but it is most commonly extracted and incorporated into tinctures and other capsules. THCA capsules are typically taken sublingually or under the tongue, where they can quickly and accurately be dosed. When THCA is heated, it loses its carboxyl group and converts it into THC through decarboxylation. It can occur when you smoke a fat blunt or juice your raw cannabis, but it can also happen naturally over time as the plant ages. While THCA is not psychoactive and does not cause any high, it can trigger a positive drug test result because it will be converted to THC in the urine. As a result, it is recommended that you do not consume any form of THCA if you are scheduled for a workplace drug test.
THCA Is More Bioavailable than CBD
THCA is the most psychoactive precursor to THC but offers unique therapeutic benefits. The molecule is being studied for its ability to reduce anxiety and depression by triggering serotonin receptors directly. It can also act as an appetite stimulant and can alleviate pain. Interestingly, THCA does not produce a high when consumed raw. Its molecular structure prevents it from binding with CB receptors in our endocannabinoid system to cause an intoxicating effect. The only way to experience THCA at its full potential is by smoking or vaping cannabis that has undergone decarboxylation. This process involves heating the cannabis to remove its extra carboxyl ring. You can also consume THCA via juiced raw cannabis or a THCA-based supplement, like a tincture. However, even if you smoke or vape a cannabis product that has undergone decarboxylation, the compound won’t remain THCA for long. Once THCA is exposed to heat, it will immediately convert into THC. That is why using a high-quality product lab-tested for potency with either liquid chromatography or gas chromatography is important. Both methods require the sample to be heated. THCA can also be converted into Delta 10 (mildly psychoactive tetrahydrocannabinol) and the intoxicating tetrahydrocannabinol CBD, which both have a similar structure to THC but lack its carboxylic acid group. THCA and delta 10 are metabolites of THC, meaning they can appear on a drug test for marijuana.
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